Efficient Assessment of Developmental, Surgical and Pathological Lymphangiogenesis Using a Lymphatic Reporter Mouse and Its Embryonic Stem Cells
Identifieur interne : 001122 ( Main/Exploration ); précédent : 001121; suivant : 001123Efficient Assessment of Developmental, Surgical and Pathological Lymphangiogenesis Using a Lymphatic Reporter Mouse and Its Embryonic Stem Cells
Auteurs : Mingu Hong [États-Unis] ; Eunson Jung [États-Unis] ; Sara Yang [États-Unis] ; Wonhyuek Jung [États-Unis] ; Young Jin Seong [États-Unis] ; Eunkyung Park [États-Unis] ; Athanasios Bramos [États-Unis] ; Kyu Eui Kim [États-Unis] ; Sunju Lee [États-Unis] ; George Daghlian [États-Unis] ; Jung In Seo [États-Unis] ; Inho Choi [États-Unis, Corée du Sud] ; In-Seon Choi [États-Unis] ; Chester J. Koh [États-Unis] ; Agnieszka Kobielak [Pologne] ; Qi-Long Ying [États-Unis] ; Maxwell Johnson [États-Unis] ; Daniel Gardner [États-Unis] ; Alex K. Wong [États-Unis] ; Dongwon Choi [États-Unis] ; Young-Kwon Hong [États-Unis]Source :
- PLoS ONE [ 1932-6203 ] ; 2016.
Abstract
Several lymphatic reporter mouse lines have recently been developed to significantly improve imaging of lymphatic vessels. Nonetheless, the usage of direct visualization of lymphatic vessels has not been fully explored and documented. Here, we characterized a new Prox1-tdTomato transgenic lymphatic reporter mouse line, and demonstrated how this animal tool enables the researchers to efficiently assess developmental, surgical and pathological lymphangiogenesis by direct visualization of lymphatic vessels. Moreover, we have derived embryonic stem cells from this reporter line, and successfully differentiated them into lymphatic vessels
Url:
DOI: 10.1371/journal.pone.0157126
PubMed: 27280889
PubMed Central: 4900649
Affiliations:
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Sud</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="aff002"><addr-line>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Jung, Eunson" sort="Jung, Eunson" uniqKey="Jung E" first="Eunson" last="Jung">Eunson Jung</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of 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Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="aff002"><addr-line>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Jung, Wonhyuek" sort="Jung, Wonhyuek" uniqKey="Jung W" first="Wonhyuek" last="Jung">Wonhyuek Jung</name><affiliation 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xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Seong, Young Jin" sort="Seong, Young Jin" uniqKey="Seong Y" first="Young Jin" last="Seong">Young Jin Seong</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, 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Sud</orgName></affiliation></author><author><name sortKey="Park, Eunkyung" sort="Park, Eunkyung" uniqKey="Park E" first="Eunkyung" last="Park">Eunkyung Park</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="aff002"><addr-line>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Bramos, Athanasios" sort="Bramos, Athanasios" uniqKey="Bramos A" first="Athanasios" last="Bramos">Athanasios Bramos</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country 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Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="aff002"><addr-line>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Lee, Sunju" sort="Lee, Sunju" uniqKey="Lee S" first="Sunju" last="Lee">Sunju Lee</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="aff002"><addr-line>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Daghlian, George" sort="Daghlian, George" uniqKey="Daghlian G" first="George" last="Daghlian">George Daghlian</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="aff002"><addr-line>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Seo, Jung In" sort="Seo, Jung In" uniqKey="Seo J" first="Jung In" last="Seo">Jung In Seo</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="aff002"><addr-line>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Choi, Inho" sort="Choi, Inho" uniqKey="Choi I" first="Inho" last="Choi">Inho Choi</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation><affiliation wicri:level="1"><nlm:aff id="aff003"><addr-line>Department of Pharmaceutical Engineering, Hoseo University, Asan, Republic of Korea</addr-line></nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Pharmaceutical Engineering, Hoseo University, Asan</wicri:regionArea><wicri:noRegion>Asan</wicri:noRegion></affiliation></author><author><name sortKey="Choi, In Seon" sort="Choi, In Seon" uniqKey="Choi I" first="In-Seon" last="Choi">In-Seon Choi</name><affiliation wicri:level="2"><nlm:aff id="aff004"><addr-line>Division of Pediatric Urology, Texas Children’s Hospital, Baylor College of Medicine, Houston, Texas, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Pediatric Urology, Texas Children’s Hospital, Baylor College of Medicine, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Koh, Chester J" sort="Koh, Chester J" uniqKey="Koh C" first="Chester J." last="Koh">Chester J. Koh</name><affiliation wicri:level="2"><nlm:aff id="aff004"><addr-line>Division of Pediatric Urology, Texas Children’s Hospital, Baylor College of Medicine, Houston, Texas, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Pediatric Urology, Texas Children’s Hospital, Baylor College of Medicine, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Kobielak, Agnieszka" sort="Kobielak, Agnieszka" uniqKey="Kobielak A" first="Agnieszka" last="Kobielak">Agnieszka Kobielak</name><affiliation wicri:level="1"><nlm:aff id="aff005"><addr-line>Centre of New Technologies, University of Warsaw, S. Banacha 2c, Room 2107, Warsaw, Poland</addr-line></nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>Centre of New Technologies, University of Warsaw, S. Banacha 2c, Room 2107, Warsaw</wicri:regionArea><wicri:noRegion>Warsaw</wicri:noRegion></affiliation></author><author><name sortKey="Ying, Qi Long" sort="Ying, Qi Long" uniqKey="Ying Q" first="Qi-Long" last="Ying">Qi-Long Ying</name><affiliation wicri:level="4"><nlm:aff id="aff006"><addr-line>Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Department of Stem Cell Biology & Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Department of Stem Cell Biology & Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Johnson, Maxwell" sort="Johnson, Maxwell" uniqKey="Johnson M" first="Maxwell" last="Johnson">Maxwell Johnson</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Gardner, Daniel" sort="Gardner, Daniel" uniqKey="Gardner D" first="Daniel" last="Gardner">Daniel Gardner</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Wong, Alex K" sort="Wong, Alex K" uniqKey="Wong A" first="Alex K." last="Wong">Alex K. Wong</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Choi, Dongwon" sort="Choi, Dongwon" uniqKey="Choi D" first="Dongwon" last="Choi">Dongwon Choi</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="aff002"><addr-line>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Hong, Young Kwon" sort="Hong, Young Kwon" uniqKey="Hong Y" first="Young-Kwon" last="Hong">Young-Kwon Hong</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="aff002"><addr-line>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27280889</idno><idno type="pmc">4900649</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900649</idno><idno type="RBID">PMC:4900649</idno><idno type="doi">10.1371/journal.pone.0157126</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">000841</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000841</idno><idno type="wicri:Area/Pmc/Curation">000841</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000841</idno><idno type="wicri:Area/Pmc/Checkpoint">000A01</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000A01</idno><idno type="wicri:Area/Ncbi/Merge">008406</idno><idno type="wicri:Area/Ncbi/Curation">008406</idno><idno type="wicri:Area/Ncbi/Checkpoint">008406</idno><idno type="wicri:Area/Main/Merge">001124</idno><idno type="wicri:Area/Main/Curation">001122</idno><idno type="wicri:Area/Main/Exploration">001122</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Efficient Assessment of Developmental, Surgical and Pathological Lymphangiogenesis Using a Lymphatic Reporter Mouse and Its Embryonic Stem Cells</title><author><name sortKey="Hong, Mingu" sort="Hong, Mingu" uniqKey="Hong M" first="Mingu" last="Hong">Mingu Hong</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="aff002"><addr-line>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Jung, Eunson" sort="Jung, Eunson" uniqKey="Jung E" first="Eunson" last="Jung">Eunson Jung</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="aff002"><addr-line>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Yang, Sara" sort="Yang, Sara" uniqKey="Yang S" first="Sara" last="Yang">Sara Yang</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="aff002"><addr-line>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Jung, Wonhyuek" sort="Jung, Wonhyuek" uniqKey="Jung W" first="Wonhyuek" last="Jung">Wonhyuek Jung</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="aff002"><addr-line>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Seong, Young Jin" sort="Seong, Young Jin" uniqKey="Seong Y" first="Young Jin" last="Seong">Young Jin Seong</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="aff002"><addr-line>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Park, Eunkyung" sort="Park, Eunkyung" uniqKey="Park E" first="Eunkyung" last="Park">Eunkyung Park</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="aff002"><addr-line>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Bramos, Athanasios" sort="Bramos, Athanasios" uniqKey="Bramos A" first="Athanasios" last="Bramos">Athanasios Bramos</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Kim, Kyu Eui" sort="Kim, Kyu Eui" uniqKey="Kim K" first="Kyu Eui" last="Kim">Kyu Eui Kim</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="aff002"><addr-line>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Lee, Sunju" sort="Lee, Sunju" uniqKey="Lee S" first="Sunju" last="Lee">Sunju Lee</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="aff002"><addr-line>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Daghlian, George" sort="Daghlian, George" uniqKey="Daghlian G" first="George" last="Daghlian">George Daghlian</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="aff002"><addr-line>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Seo, Jung In" sort="Seo, Jung In" uniqKey="Seo J" first="Jung In" last="Seo">Jung In Seo</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="aff002"><addr-line>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Choi, Inho" sort="Choi, Inho" uniqKey="Choi I" first="Inho" last="Choi">Inho Choi</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation><affiliation wicri:level="1"><nlm:aff id="aff003"><addr-line>Department of Pharmaceutical Engineering, Hoseo University, Asan, Republic of Korea</addr-line></nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Pharmaceutical Engineering, Hoseo University, Asan</wicri:regionArea><wicri:noRegion>Asan</wicri:noRegion></affiliation></author><author><name sortKey="Choi, In Seon" sort="Choi, In Seon" uniqKey="Choi I" first="In-Seon" last="Choi">In-Seon Choi</name><affiliation wicri:level="2"><nlm:aff id="aff004"><addr-line>Division of Pediatric Urology, Texas Children’s Hospital, Baylor College of Medicine, Houston, Texas, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Pediatric Urology, Texas Children’s Hospital, Baylor College of Medicine, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Koh, Chester J" sort="Koh, Chester J" uniqKey="Koh C" first="Chester J." last="Koh">Chester J. Koh</name><affiliation wicri:level="2"><nlm:aff id="aff004"><addr-line>Division of Pediatric Urology, Texas Children’s Hospital, Baylor College of Medicine, Houston, Texas, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Pediatric Urology, Texas Children’s Hospital, Baylor College of Medicine, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Kobielak, Agnieszka" sort="Kobielak, Agnieszka" uniqKey="Kobielak A" first="Agnieszka" last="Kobielak">Agnieszka Kobielak</name><affiliation wicri:level="1"><nlm:aff id="aff005"><addr-line>Centre of New Technologies, University of Warsaw, S. Banacha 2c, Room 2107, Warsaw, Poland</addr-line></nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>Centre of New Technologies, University of Warsaw, S. Banacha 2c, Room 2107, Warsaw</wicri:regionArea><wicri:noRegion>Warsaw</wicri:noRegion></affiliation></author><author><name sortKey="Ying, Qi Long" sort="Ying, Qi Long" uniqKey="Ying Q" first="Qi-Long" last="Ying">Qi-Long Ying</name><affiliation wicri:level="4"><nlm:aff id="aff006"><addr-line>Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Department of Stem Cell Biology & Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Department of Stem Cell Biology & Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Johnson, Maxwell" sort="Johnson, Maxwell" uniqKey="Johnson M" first="Maxwell" last="Johnson">Maxwell Johnson</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Gardner, Daniel" sort="Gardner, Daniel" uniqKey="Gardner D" first="Daniel" last="Gardner">Daniel Gardner</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Wong, Alex K" sort="Wong, Alex K" uniqKey="Wong A" first="Alex K." last="Wong">Alex K. Wong</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Choi, Dongwon" sort="Choi, Dongwon" uniqKey="Choi D" first="Dongwon" last="Choi">Dongwon Choi</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="aff002"><addr-line>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Hong, Young Kwon" sort="Hong, Young Kwon" uniqKey="Hong Y" first="Young-Kwon" last="Hong">Young-Kwon Hong</name><affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="aff002"><addr-line>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author></analytic><series><title level="j">PLoS ONE</title><idno type="eISSN">1932-6203</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Several lymphatic reporter mouse lines have recently been developed to significantly improve imaging of lymphatic vessels. Nonetheless, the usage of direct visualization of lymphatic vessels has not been fully explored and documented. Here, we characterized a new Prox1-tdTomato transgenic lymphatic reporter mouse line, and demonstrated how this animal tool enables the researchers to efficiently assess developmental, surgical and pathological lymphangiogenesis by direct visualization of lymphatic vessels. Moreover, we have derived embryonic stem cells from this reporter line, and successfully differentiated them into lymphatic vessels <italic>in vivo</italic>. In conclusion, these experimental tools and techniques will help advance lymphatic research.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Motoike, T" uniqKey="Motoike T">T Motoike</name></author><author><name sortKey="Loughna, S" uniqKey="Loughna S">S Loughna</name></author><author><name sortKey="Perens, E" uniqKey="Perens E">E Perens</name></author><author><name sortKey="Roman, Bl" uniqKey="Roman B">BL Roman</name></author><author><name sortKey="Liao, W" uniqKey="Liao W">W Liao</name></author><author><name sortKey="Chau, Tc" uniqKey="Chau T">TC Chau</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Iljin, K" uniqKey="Iljin K">K Iljin</name></author><author><name sortKey="Karkkainen, Mj" uniqKey="Karkkainen M">MJ Karkkainen</name></author><author><name sortKey="Lawrence, Ec" uniqKey="Lawrence E">EC Lawrence</name></author><author><name sortKey="Kimak, Ma" uniqKey="Kimak M">MA 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sortKey="Bramos, Athanasios" sort="Bramos, Athanasios" uniqKey="Bramos A" first="Athanasios" last="Bramos">Athanasios Bramos</name><name sortKey="Choi, Dongwon" sort="Choi, Dongwon" uniqKey="Choi D" first="Dongwon" last="Choi">Dongwon Choi</name><name sortKey="Choi, Dongwon" sort="Choi, Dongwon" uniqKey="Choi D" first="Dongwon" last="Choi">Dongwon Choi</name><name sortKey="Choi, In Seon" sort="Choi, In Seon" uniqKey="Choi I" first="In-Seon" last="Choi">In-Seon Choi</name><name sortKey="Choi, Inho" sort="Choi, Inho" uniqKey="Choi I" first="Inho" last="Choi">Inho Choi</name><name sortKey="Daghlian, George" sort="Daghlian, George" uniqKey="Daghlian G" first="George" last="Daghlian">George Daghlian</name><name sortKey="Daghlian, George" sort="Daghlian, George" uniqKey="Daghlian G" first="George" last="Daghlian">George Daghlian</name><name sortKey="Gardner, Daniel" sort="Gardner, Daniel" uniqKey="Gardner D" first="Daniel" last="Gardner">Daniel Gardner</name><name sortKey="Hong, Mingu" sort="Hong, Mingu" uniqKey="Hong M" first="Mingu" last="Hong">Mingu Hong</name><name sortKey="Hong, Young Kwon" sort="Hong, Young Kwon" uniqKey="Hong Y" first="Young-Kwon" last="Hong">Young-Kwon Hong</name><name sortKey="Hong, Young Kwon" sort="Hong, Young Kwon" uniqKey="Hong Y" first="Young-Kwon" last="Hong">Young-Kwon Hong</name><name sortKey="Johnson, Maxwell" sort="Johnson, Maxwell" uniqKey="Johnson M" first="Maxwell" last="Johnson">Maxwell Johnson</name><name sortKey="Jung, Eunson" sort="Jung, Eunson" uniqKey="Jung E" first="Eunson" last="Jung">Eunson Jung</name><name sortKey="Jung, Eunson" sort="Jung, Eunson" uniqKey="Jung E" first="Eunson" last="Jung">Eunson Jung</name><name sortKey="Jung, Wonhyuek" sort="Jung, Wonhyuek" uniqKey="Jung W" first="Wonhyuek" last="Jung">Wonhyuek Jung</name><name sortKey="Jung, Wonhyuek" sort="Jung, Wonhyuek" uniqKey="Jung W" first="Wonhyuek" last="Jung">Wonhyuek Jung</name><name sortKey="Kim, Kyu Eui" sort="Kim, Kyu Eui" uniqKey="Kim K" first="Kyu Eui" last="Kim">Kyu Eui Kim</name><name sortKey="Kim, Kyu Eui" sort="Kim, Kyu Eui" uniqKey="Kim K" first="Kyu Eui" last="Kim">Kyu Eui Kim</name><name sortKey="Koh, Chester J" sort="Koh, Chester J" uniqKey="Koh C" first="Chester J." last="Koh">Chester J. Koh</name><name sortKey="Lee, Sunju" sort="Lee, Sunju" uniqKey="Lee S" first="Sunju" last="Lee">Sunju Lee</name><name sortKey="Lee, Sunju" sort="Lee, Sunju" uniqKey="Lee S" first="Sunju" last="Lee">Sunju Lee</name><name sortKey="Park, Eunkyung" sort="Park, Eunkyung" uniqKey="Park E" first="Eunkyung" last="Park">Eunkyung Park</name><name sortKey="Park, Eunkyung" sort="Park, Eunkyung" uniqKey="Park E" first="Eunkyung" last="Park">Eunkyung Park</name><name sortKey="Seo, Jung In" sort="Seo, Jung In" uniqKey="Seo J" first="Jung In" last="Seo">Jung In Seo</name><name sortKey="Seo, Jung In" sort="Seo, Jung In" uniqKey="Seo J" first="Jung In" last="Seo">Jung In Seo</name><name sortKey="Seong, Young Jin" sort="Seong, Young Jin" uniqKey="Seong Y" first="Young Jin" last="Seong">Young Jin Seong</name><name sortKey="Seong, Young Jin" sort="Seong, Young Jin" uniqKey="Seong Y" first="Young Jin" last="Seong">Young Jin Seong</name><name sortKey="Wong, Alex K" sort="Wong, Alex K" uniqKey="Wong A" first="Alex K." last="Wong">Alex K. Wong</name><name sortKey="Yang, Sara" sort="Yang, Sara" uniqKey="Yang S" first="Sara" last="Yang">Sara Yang</name><name sortKey="Yang, Sara" sort="Yang, Sara" uniqKey="Yang S" first="Sara" last="Yang">Sara Yang</name><name sortKey="Ying, Qi Long" sort="Ying, Qi Long" uniqKey="Ying Q" first="Qi-Long" last="Ying">Qi-Long Ying</name></country><country name="Corée du Sud"><noRegion><name sortKey="Choi, Inho" sort="Choi, Inho" uniqKey="Choi I" first="Inho" last="Choi">Inho Choi</name></noRegion></country><country name="Pologne"><noRegion><name sortKey="Kobielak, Agnieszka" sort="Kobielak, Agnieszka" uniqKey="Kobielak A" first="Agnieszka" last="Kobielak">Agnieszka Kobielak</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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